Academic Journal
Q2Toxicology and Applied Pharmacology
About Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology is a scholarly journal published by Academic Press Inc.. SCImago 2025 places it in Q2 with an SJR of 0.911 and an H-index of 199.
Its listed coverage is 1959-2026 and its research categories include Pharmacology (Q2); Toxicology (Q2). The 2025 dataset reports 345 documents and 3175 citations across the latest three-year reporting window.
Journal Metrics
Metrics can change by reporting year. Verify time-sensitive values with the publisher or indexing service.
Aims & Scope
The journal publishes research related to Carcinogens and Genotoxicity Assessment, Heavy Metal Exposure and Toxicity, Diverse Scientific and Economic Studies, Effects and risks of endocrine disrupting chemicals, Pharmacogenetics and Drug Metabolism, Pesticide Exposure and Toxicity.
Recent Research Articles
Latest publications matched automatically by ISSN.
Inhibition of Calpain-1 ameliorates doxorubicin-induced cardiotoxicity by suppression of p53-mediated ferroptosis
Zhuo Zhang, Xinbin Zheng, Dabao Xiao, Mengya Zeng et al.
2026-11 · DOI: 10.1016/j.taap.2026.118001Physiologically based pharmacokinetic modeling of propofol: Impact of liver cirrhosis on systemic exposure and model-informed dose optimization according to Child–Pugh classification
Hee-Yeong Jeong, Chi-Ho Lee, Ji-Hun Jang, Seung-Hyun Jeong et al.
2026-11 · DOI: 10.1016/j.taap.2026.118016Mitochondrial complex I and II inhibiting pesticides activate DELE1-HRI integrated stress signaling but engage distinct cell death programs in human neuronal cells
Hanen Chaabani, Damien Arnoult, Joel Eyer, Karima Rjiba et al.
2026-11 · DOI: 10.1016/j.taap.2026.117991ΔA146Ply exerts anti-triple-negative breast cancer effects by inducing ferroptosis via regulation of the CYP24A1-mediated calcitriol-vitamin D receptor pathway
Ye Yu, Zhengkun Zhang, Dingxue Wang, Xin Bai et al.
2026-11 · DOI: 10.1016/j.taap.2026.118025Mitochondrial sensitivity to Ca2+-induced permeability transition in mouse liver exhibits time-of-day dependence
Tomoyuki Sato, Kohei Yamaguchi, Taira Wada, Shigeki Shimba et al.
2026-11 · DOI: 10.1016/j.taap.2026.117997Identification of candidate microRNA biomarkers of mouse cholangiocyte injury by global miRNAome analysis
Lawrence Howell, Joseph P. Brown, Shiva Seyed Forootan, Ben Francis et al.
2026-11 · DOI: 10.1016/j.taap.2026.117998Bisphenol A and F exposure suppresses MMP9 to drive nasal epithelial inflammation and senescence: a protective target for allergic rhinitis
Min Liu, Tianxin Zhao, Yijun Liu, Hua Yang et al.
2026-11 · DOI: 10.1016/j.taap.2026.118017Irisin restores testicular metabolic homeostasis and spermatogenesis against chronic unpredictable stress in rats: An integrated 1H NMR metabolomics and molecular study
Itishree Dubey, Gurvinder Singh, Dinesh Kumar, Sapana Kushwaha et al.
2026-11 · DOI: 10.1016/j.taap.2026.118019Polystyrene nanoplastics exposure induces reproductive toxicity in male mice associated with the gut–liver/testis axis
Fahao Hou, Yan Xuan, Tengxiao Liu, Yue Jiang et al.
2026-11 · DOI: 10.1016/j.taap.2026.118022Anti-colorectal cancer activity of sertraline in mice involves regulation of arachidonic acid metabolism revealed by UPLC-Q Exactive Orbitrap MS-based metabolomics
Yihong Shen, Leping He, Chenglong Zheng, Dongmeng Liu et al.
2026-11 · DOI: 10.1016/j.taap.2026.118021RAB17 downregulation elicits antitumor impacts in prostate cancer by triggering ferroptotic cell death through the regulation of TfR1-mediated iron overload
Dongli Ruan, Wanghui Su, Yang Zhang, Xiulong Ma et al.
2026-11 · DOI: 10.1016/j.taap.2026.118023Betaine alleviates scleral remodeling in experimental myopia by regulating the TLR4/TAK1/NF-κB signaling pathway
Yinqiao Zhang, Yunxiao Xie, Zhaohui Yang, Runze Gao et al.
2026-11 · DOI: 10.1016/j.taap.2026.117992Release of bound steroid from the androgen and estrogen receptors is induced by DDT and its analogs
Matthew D. Rosales, Tahyra Soto, Jacqueline I. Goodship, Ahyssa R. Cruz et al.
2026-11 · DOI: 10.1016/j.taap.2026.118015Tannic acid protects against lapatinib-induced hepatotoxicity by inhibiting cathepsin activity and repairing lysosomal membrane permeabilization
Yuan Mu, Zengyue Pan, He Zhao, Xiangliang Huang et al.
2026-11 · DOI: 10.1016/j.taap.2026.118028Salvigenin alleviates diabetic nephropathy through Nrf2-mediated modulation of renal inflammation and ferroptosis
Xiaoxu Ge, Juan Du, Jiajia Wang, Liuqing Xi et al.
2026-11 · DOI: 10.1016/j.taap.2026.118000Differential hepatotoxic effects of single versus repeated MCLR exposure in control diet and high fat, high cholesterol diet fed rats
Victor O. Ikumawoyi, Tarana Arman, Katherine D. Hart, J. Allen Baron et al.
2026-11 · DOI: 10.1016/j.taap.2026.118018Untargeted serum lipidomics reveals lipid metabolic disturbances and identifies candidate lipid biomarkers in acute diquat poisoning
Xinxin Huang, Xunan Kan, Lei Xiao, Chuanguang Han et al.
2026-11 · DOI: 10.1016/j.taap.2026.117995Neuroprotective effect of miR-519a-3p downregulation against sevoflurane-induced cognitive dysfunction via regulating ESR1
Weiwei Lin, Dan Yu, Xiating Shi, Wanchao Liu et al.
2026-11 · DOI: 10.1016/j.taap.2026.118002Surface modification as a strategy to mitigate TiO₂ NPs-induced neurotoxicity in rats
Israa Elhussein, Eman I. Hassanen, Khaled Y. Farroh, Rehab A. Azouz et al.
2026-11 · DOI: 10.1016/j.taap.2026.118024Loss of MEG3 promotes migration and invasion of nickel-transformed cells, partially via upregulation of RUNX2
Bo Yan, Zhuo Zhang, Jingxia Li, Max Costa et al.
2026-11 · DOI: 10.1016/j.taap.2026.118026Reviews
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September 8, 2026 at 12:09 am
September 8, 2026