Journal Name: Clinical Cancer Research
Journal Type: Q1
ISSN: 10780432, 15573265
Country: United States
Subject Area and Category: Biochemistry, Genetics and Molecular Biology Cancer Research Medicine Oncology
Research Ranking: 22
Publication Type: Journals
H-Index: 392
Coverage: 1995-2025
Editors-in-Chief: Timothy A. Yap
Research Impact Score: 40.1
Impact Factor: 10
SCIMAGO SJR: 4.800
APC Cost: $8000
Homepage: https://clincancerres.aacrjournals.org/
Submission Link: https://clincancerres.aacrjournals.org/
Contact Email: ccr@aacr.org
Address: American Association for Cancer Research (AACR) Attn: Clinical Cancer Research 615 Chestnut Street, 17th Floor Philadelphia, PA 19106-4404 USA
Overview
Clinical Cancer Research: Advancing the Frontiers of Oncology
Clinical Cancer Research is a leading peer-reviewed journal dedicated to publishing impactful studies that bridge the gap between laboratory research and clinical practice in oncology. As cancer remains a major global health challenge, the journal plays a pivotal role in disseminating cutting-edge research that drives innovation in cancer diagnosis, treatment, and prevention.
What Is Clinical Cancer Research?
Published by the American Association for Cancer Research (AACR), Clinical Cancer Research focuses on clinical trials, translational studies, and novel therapeutic strategies that directly impact patient care. The journal covers a wide range of cancer types and includes research on drug development, molecular diagnostics, biomarkers, immunotherapy, and precision medicine.
A Hub for Translational Oncology
The journal emphasizes the importance of translational research—studies that convert basic scientific discoveries into practical medical applications. This focus ensures that promising therapies move from the laboratory to clinical testing with speed and precision. As a result, Clinical Cancer Research serves as a crucial platform for researchers, oncologists, and healthcare professionals seeking evidence-based insights into cancer management.
Key Topics and Research Areas
To maintain its relevance and high impact, the journal regularly publishes articles in areas such as:
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Targeted Therapy: Studies exploring drugs that specifically target cancer cells while sparing healthy tissues.
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Immunotherapy: Research on immune-based treatments, including checkpoint inhibitors and cancer vaccines.
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Biomarker Discovery: Investigations identifying genetic and molecular markers that predict treatment response or prognosis.
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Precision Medicine: Personalized treatment approaches based on individual genetic profiles.
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Early Detection and Screening: Advances in diagnostic tools for earlier cancer identification.
Importance in the Oncology Community
With an impressive impact factor and a rigorous peer-review process, Clinical Cancer Research is a trusted source of scientific knowledge. Its contributions help shape clinical guidelines, inform policy decisions, and support the ongoing development of more effective cancer therapies.
Accessibility and Global Reach
The journal attracts submissions from leading cancer centers around the world and reaches a global audience of oncology professionals. Online accessibility and indexing in major databases such as PubMed, Scopus, and Web of Science enhance its visibility and influence.
Why Clinical Cancer Research Matters
In a time when personalized and data-driven approaches are revolutionizing cancer care, Clinical Cancer Research stands at the forefront of discovery. Its commitment to high-quality, clinically relevant research empowers the medical community to improve outcomes for cancer patients worldwide.
About
About Clinical Cancer Research: Advancing Hope Through Innovation
Clinical cancer research plays a critical role in the ongoing fight against cancer. It involves the study of cancer treatment and prevention through carefully designed clinical trials, aiming to improve patient outcomes, discover more effective therapies, and deepen our understanding of cancer biology. As cancer remains one of the leading causes of death worldwide, clinical research stands as a beacon of hope, offering new possibilities for early detection, targeted treatments, and potential cures.
What Is Clinical Cancer Research?
Clinical cancer research refers to the scientific studies conducted on human participants to evaluate the effectiveness, safety, and side effects of new cancer treatments. These can include drugs, medical devices, biological therapies, or surgical techniques. The ultimate goal is to find better ways to treat cancer, enhance quality of life, and extend survival rates.
Research typically progresses through several phases:
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Phase I focuses on determining a safe dosage and identifying side effects.
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Phase II assesses the treatment’s effectiveness.
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Phase III compares the new treatment with the current standard of care.
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Phase IV takes place after FDA approval to monitor long-term effects.
Importance of Clinical Cancer Research
Clinical cancer research is vital because it translates laboratory discoveries into life-saving treatments. Through clinical trials, researchers can test breakthrough therapies, such as immunotherapy, precision medicine, and gene editing, that have the potential to revolutionize cancer care.
Additionally, clinical research enables:
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Improved survival rates by offering patients access to cutting-edge treatments before they’re widely available.
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Personalized medicine by tailoring therapies to individual genetic profiles.
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Better understanding of cancer progression, resistance, and recurrence.
Recent Advancements in Cancer Research
Thanks to continuous clinical research, there have been significant advancements in cancer treatment over the past decade. Immunotherapies, like checkpoint inhibitors and CAR T-cell therapy, have shown remarkable success in treating cancers previously considered untreatable. Targeted therapies, designed to attack specific cancer cells while sparing healthy ones, are changing the landscape of cancer care.
Moreover, liquid biopsies and biomarker testing are improving early detection and monitoring of cancer, leading to more proactive and precise interventions.
How to Participate in Clinical Trials
Patients interested in joining a clinical trial should consult with their oncologist to understand their options. Participation is voluntary and involves a detailed informed consent process. Clinical trials are conducted under strict ethical and safety guidelines to protect participants.
Websites like ClinicalTrials.gov offer searchable databases for ongoing studies across the globe.
Scope
Scope of Clinical Cancer Research: Advancing the Future of Oncology
Clinical cancer research plays a pivotal role in the ongoing fight against cancer. This dynamic field focuses on translating basic scientific discoveries into practical therapies, improving diagnostics, and enhancing patient care. As cancer remains one of the leading causes of death worldwide, the scope of clinical cancer research continues to expand, driven by technological advancements, personalized medicine, and a deeper understanding of cancer biology.
What Is Clinical Cancer Research?
Clinical cancer research involves studies conducted with cancer patients or healthy volunteers aimed at evaluating new treatments, improving current therapies, and uncovering the mechanisms behind cancer development. These studies range from early-phase clinical trials testing the safety of novel drugs to large-scale randomized controlled trials assessing treatment efficacy.
The ultimate goal is to develop safe, effective, and targeted therapies that improve survival rates and quality of life for cancer patients. Clinical cancer research bridges the gap between laboratory findings and real-world treatment, ensuring that scientific innovations are translated into meaningful clinical outcomes.
Key Areas Within Clinical Cancer Research
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Early Detection and Diagnosis
Research into improved screening tools and diagnostic imaging is crucial. Early detection of cancer significantly increases the chances of successful treatment. Clinical studies evaluate new biomarkers, genetic tests, and imaging technologies that help diagnose cancers at an earlier, more treatable stage. -
Targeted Therapies and Immunotherapy
One of the most exciting areas in cancer research is the development of targeted therapies and immunotherapies. These treatments aim to attack cancer cells while minimizing harm to healthy tissues. Clinical trials are essential in testing the safety and efficacy of these cutting-edge approaches. -
Personalized Medicine
Precision oncology uses genetic and molecular profiling to tailor treatments to individual patients. Clinical research enables oncologists to identify which therapies are most likely to benefit specific subgroups of patients, reducing trial-and-error treatment and improving outcomes. -
Survivorship and Quality of Life
As survival rates improve, research also focuses on the long-term effects of cancer treatment. Clinical studies explore ways to reduce side effects, manage symptoms, and support the mental and emotional well-being of survivors. -
Prevention and Risk Reduction
Clinical research isn’t only about treating cancer—it also plays a key role in prevention. Studies assess the effectiveness of vaccines, lifestyle interventions, and medications in reducing cancer risk among high-risk populations.
The Importance of Clinical Trials
Clinical trials are at the heart of clinical cancer research. They are the gold standard for evaluating new treatments and improving current protocols. Participation in clinical trials allows patients to access promising new therapies before they become widely available.