Academic Journal
Q1Science Translational Medicine
About Science Translational Medicine
Science Translational Medicine is a scholarly journal published by American Association for the Advancement of Science. SCImago 2025 places it in Q1 with an SJR of 7.026 and an H-index of 321.
Its listed coverage is 2009-2026 and its research categories include Medicine (miscellaneous) (Q1). The 2025 dataset reports 324 documents and 14007 citations across the latest three-year reporting window.
Science Translational Medicine: Driving Innovation from Bench to Bedside
Science Translational Medicine is a premier peer-reviewed journal that plays a crucial role in advancing the field of biomedical research. Published by the American Association for the Advancement of Science (AAAS), this influential journal is dedicated to accelerating the translation of scientific discoveries into effective medical treatments, diagnostics, and healthcare innovations. It serves as a vital link between laboratory research and clinical application, helping bridge the gap between science and medicine.
What is Science Translational Medicine?
Science Translational Medicine focuses on translational research, which is the process of turning basic scientific discoveries into practical solutions that can improve patient care. The journal publishes groundbreaking research articles, clinical studies, commentaries, and perspectives that explore how innovations in biology, chemistry, physics, and engineering can be applied in a clinical context.
Since its launch in 2009, the journal has gained global recognition for its high standards of scientific excellence, interdisciplinary approach, and real-world impact. It caters to a diverse audience, including scientists, medical professionals, academic researchers, pharmaceutical companies, and healthcare policymakers.
Focus Areas of Science Translational Medicine
The journal covers a wide range of topics at the intersection of science and medicine. Key focus areas include:
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Personalized medicine and genomics
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Immunotherapy and cancer research
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Gene therapy and regenerative medicine
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Infectious diseases and vaccine development
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Neuroscience and mental health research
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Biomarker discovery and diagnostic innovation
Each published study is selected for its potential to transform medical practices or significantly advance our understanding of human health and disease.
Why Science Translational Medicine Matters
In today’s rapidly evolving healthcare landscape, the need to quickly and effectively translate research findings into real-world solutions is more important than ever. Science Translational Medicine provides a trusted platform for disseminating studies that are not only scientifically rigorous but also clinically relevant.
The journal helps:
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Accelerate drug development by showcasing promising new therapies
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Improve clinical outcomes through better diagnostics and treatment strategies
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Foster interdisciplinary collaboration among researchers, clinicians, and industry professionals
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Support evidence-based medicine by highlighting research with direct clinical implications
By publishing high-impact research, the journal plays a significant role in shaping the future of medicine and promoting innovation across the healthcare ecosystem.
A Global Resource for Innovation
Science Translational Medicine is indexed in major databases like PubMed and Scopus, ensuring global visibility and accessibility. With a strong emphasis on collaboration, transparency, and innovation, the journal continues to influence how research is conducted, evaluated, and applied in medical settings.
Whether you're a researcher looking for the latest advances in translational science or a clinician seeking evidence-based innovations, Science Translational Medicine is an essential resource for staying at the forefront of modern medicine.
Journal Metrics
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Aims & Scope
Scope of Science Translational Medicine: Bridging Discovery and Clinical Impact
Science Translational Medicine is a leading journal published by the American Association for the Advancement of Science (AAAS), designed to accelerate the journey of scientific discovery from the research bench to clinical practice. With a strong emphasis on translational research, the journal covers a wide array of interdisciplinary studies that demonstrate how basic scientific findings can be applied to improve human health.
This article explores the comprehensive scope of Science Translational Medicine, making it clear why the journal is essential reading for researchers, clinicians, and industry professionals working at the interface of science and medicine.
Core Mission and Focus
The core mission of Science Translational Medicine is to advance human health by facilitating the translation of basic science into medical applications. Its scope spans the entire translational spectrum—from laboratory experiments to preclinical studies, clinical trials, and real-world implementation.
The journal aims to:
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Highlight transformative research with direct clinical relevance
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Promote innovation in diagnostics, therapeutics, and preventive strategies
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Encourage cross-disciplinary collaboration between basic scientists and clinicians
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Address barriers in the translation process, including regulatory, ethical, and logistical challenges
Interdisciplinary Scope and Topics Covered
One of the journal’s strengths is its interdisciplinary scope, integrating insights from a broad range of fields. The research published in Science Translational Medicine typically falls into one or more of the following areas:
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Molecular and Cellular Biology: Studies that uncover disease mechanisms and molecular targets for therapy.
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Genomics and Precision Medicine: Research focused on tailoring treatments based on genetic profiles and biomarkers.
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Pharmacology and Drug Development: New drug candidates, repurposing of existing drugs, and novel delivery systems.
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Immunology and Inflammation: Breakthroughs in immune-based therapies, including vaccines and immunomodulators.
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Oncology: Translational cancer research, from molecular diagnostics to new therapeutic strategies.
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Neuroscience: Studies that address brain disorders, neurodegeneration, and neural repair.
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Regenerative Medicine and Tissue Engineering: Development of stem cell therapies and bioengineered tissues.
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Infectious Diseases: Innovations in antiviral drugs, antibiotics, and vaccines.
Article Types and Research Models
The journal publishes a range of article types, including:
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Original research articles
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Clinical trial reports
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Technical innovations
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Perspectives and reviews
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Policy and commentary pieces
Science Translational Medicine supports a variety of research models, including animal studies, in vitro systems, human tissue analysis, and early-phase clinical trials. Importantly, each study must demonstrate translational relevance, bridging basic findings with potential or real-world clinical impact.
Global Reach and Scientific Influence
With a high impact factor and broad readership, Science Translational Medicine has become a go-to resource for those engaged in medical innovation. Its content influences not only scientific research but also healthcare policy, biotechnology development, and clinical decision-making.
Recent Research Articles
Latest publications matched automatically by ISSN.
Metabolic reallocation in spinal cord oligodendrocytes drives chronic pain in mice through neuronal Aβ 42 production
Yannick Fotio, Saeed Al Masri, Zechuan Shi, Johnny Le et al.
2026-09-02 · DOI: 10.1126/scitranslmed.aea8738Multifunctional antibody responses from a primate Shigella outbreak inform vaccine design
Robert M. Gallant, Paul Savarino, Sophia Pulido, Morgan S. A. Gilman et al.
2026-09-02 · DOI: 10.1126/scitranslmed.aef7084MicroRNA-224 orchestrates BMP and TGFβ signaling and is a therapeutic target in preclinical pulmonary arterial hypertension
Olympia Bikou, Aymen Halouani, Yifei Sun, Malik Bisserier et al.
2026-09-02 · DOI: 10.1126/scitranslmed.aef6676Tissue origins and immune correlates of viral rebound in SIV-infected rhesus macaques after ART discontinuation
Irena V. King, Malika Aid, Emek Kose, Taina T. Immonen et al.
2026-09-02 · DOI: 10.1126/scitranslmed.aeg7776Elevated translocator protein in skull bone marrow is linked to human chronic pain
Mehrbod Mohammadian, Nikos Efthimiou, Katherin Gabriel, Ludovica Brusaferri et al.
2026-09-02 · DOI: 10.1126/scitranslmed.aed8729Sustained neutrophil extracellular traps cause fracture nonunion
Weixin Xie, Lilly-Charlotte Albertsen, Gesine Eis-Janzyk, Charlotte Kühlwein et al.
2026-09-02 · DOI: 10.1126/scitranslmed.adx9869Loss of function of ALDH3B2 transdifferentiates human pancreatic duct cells into β-like cells
Jian Li, Kevin Bode, Yu-chi Lee, Noelle Morrow et al.
2026-09-02 · DOI: 10.1126/scitranslmed.ady2234Baseline interferon signaling in monocytes and antibody-mediated innate activation are associated with reactogenicity to mRNA vaccines
Natacha Madelon, Gustavo A. Ruiz Buendía, Paula Torres Rodriguez, Yves R. Donati et al.
2026-08-26 · DOI: 10.1126/scitranslmed.aee4776Aberrant alternative splicing memorized in adipose tissue macrophages impedes efferocytosis during postobesity weight loss
Takuro Miyazaki, Akira Shiraishi, Yuki Sugiura, Eisuke Shiozawa et al.
2026-08-26 · DOI: 10.1126/scitranslmed.adv0221FUS inactivation promotes leptomeningeal metastasis of lung cancer through the up-regulation of CD36
Shouheng Lin, Kai Yin, Mei-Mei Zheng, Hai-Yan Tu et al.
2026-08-26 · DOI: 10.1126/scitranslmed.aee1083A 3D human retina model reveals a non–cell-autonomous and non-neuronal mechanism of photoreceptor loss in a lysosomal storage disorder
Jimin Han, Nathaniel Foley, Sonal Dalvi, Janet A. H. Tang et al.
2026-08-26 · DOI: 10.1126/scitranslmed.ady7616Tissue corticosteroid rhythms are dysregulated predominantly during sleep in primary aldosteronism
Marianne A. Grytaas, Thomas Upton, Isabella Marinelli, Paal Methlie et al.
2026-08-26 · DOI: 10.1126/scitranslmed.aeb7517Antibodies against MLC1 found in patients with NMOSD-like disease mediate astrocytopathy in rodent models
Hoi Kiu Wong, Samantha Ho, Qian Yu, Katherine S. Given et al.
2026-08-26 · DOI: 10.1126/scitranslmed.ady0403LTBP4 deficiency induces MRC1 + /CD44 + macrophages to drive cancer progression in preclinical colorectal cancer models
Songtao Ji, Shuya Du, Ge Miao, Xiaohua Yang et al.
2026-08-26 · DOI: 10.1126/scitranslmed.aeb2189Urogenital immune signatures are associated with birth outcomes after maternal urinary tract infection
Samantha Ottinger, Addison B. Larson, Vicki Mercado-Evans, Holly Branthoover et al.
2026-08-26 · DOI: 10.1126/scitranslmed.aea1228A population-scale transcriptional atlas of blood and tissue in lupus nephritis
Nicholas W. Sugiarto, Siddarth Gurajala, Michelle Curtis, Thomas M. Eisenhaure et al.
2026-08-19 · DOI: 10.1126/scitranslmed.aec0512Cell-free DNA fragmentome analysis informs pregnancy outcome in patients with immune-mediated disease
Kate E. Stanley, Lore Lannoo, Erika Souche, Ivo Salden et al.
2026-08-19 · DOI: 10.1126/scitranslmed.adz8846Urea transporter B–mediated urea uptake–induced protein carbamylation in platelets underlies bleeding in chronic kidney disease
Zhiwei Qiu, Fei Xiong, Zhe Wang, Yingxin Zhao et al.
2026-08-19 · DOI: 10.1126/scitranslmed.aed4678Carboxyl-terminal blockade of sortilin binding enhances progranulin gene therapy in a mouse model of frontotemporal dementia
Shreya N. Kashyap, Stephanie N. Fox, Vivianna R. DeNittis, Katherine I. Wilson et al.
2026-08-19 · DOI: 10.1126/scitranslmed.adr9158MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model
M. Catarina Silva, Hannah Lindmeier, Paolo Pigini, Jennifer Laughlin et al.
2026-08-19 · DOI: 10.1126/scitranslmed.ady6759Reviews
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April 20, 2025 at 3:01 am
April 20, 2025