2025-10-07 · arXiv (Cornell University)
Joint Embedding Predictive Architectures (JEPAs) learn representations able to solve numerous downstream tasks out-of-the-box. JEPAs combine two objectives: (i) a latent-space prediction term, i.e., the representation of a slightly perturbed sample must be predictable from…
2025-11-06 · arXiv (Cornell University)
We argue that progress in true multimodal intelligence calls for a shift from reactive, task-driven systems and brute-force long context towards a broader paradigm of supersensing. We frame spatial supersensing as four stages beyond linguistic-only…
2025-11-11 · arXiv (Cornell University)
LeJEPA replaces the heuristic machinery of modern self-supervised learning (asymmetric encoders, stop-gradients, momentum teachers, schedulers) with a single isotropic-Gaussian regulariser, SIGReg. Carrying SIGReg to sequence models exposes a documented hazard: a naive pooled application can…
2025-12-11 · arXiv (Cornell University)
We introduce VL-JEPA, a vision-language model built on a Joint Embedding Predictive Architecture (JEPA). Instead of autoregressively generating tokens as in classical VLMs, VL-JEPA predicts continuous embeddings of the target texts. By learning in an…
2025-12-15 · arXiv (Cornell University)
Modeling dexterous hand-object interactions is challenging as it requires understanding how subtle finger motions influence the environment through contact with objects. While recent world models address interaction modeling, they typically rely on coarse action spaces…
2025-12-30 · HAL (Le Centre pour la Communication Scientifique Directe)
A long-standing challenge in AI is to develop agents capable of solving a wide range of physical tasks and generalizing to new, unseen tasks and environments. A popular recent approach involves training a world model…
2026-05-20 · Nature Communications
Treatment selection in breast cancer is guided by risk assessment using molecular subtypes and clinicopathological characteristics. However, current approaches lack the precision required for optimal clinical decision-making. To address this, we use data from 8161…
2026-08-20 · Nature Communications
Abstract Foundational artificial intelligence models are gaining traction in various applications, including medical fields like radiology. However, medical foundation models are often tested on limited tasks, leaving their generalisability and biases unexplored. Here we introduce…
2025-10-21 · arXiv (Cornell University)
Imitation learning from large-scale, diverse human demonstrations has been shown to be effective for training robots, but collecting such data is costly and time-consuming. This challenge intensifies for multi-step bimanual mobile manipulation, where humans must…
2025-11-13 · Organelle
Brain organoids, as 3D cell culture models simulating human brain development and structure, have made significant progress in neuroscience research in recent years. This review systematically summarizes the current research status of brain organoids, including…
2025-11-19 · iScience
Nuclear receptors (NRs) are ligand-dependent transcription factors that play essential roles in maintaining metabolic homeostasis and regulating disease progression through the control of metabolism, inflammation, and cellular differentiation. Due to their central position in these…
2025-12-10 · npj Digital Medicine
Generative AI needs automatic clinical text accuracy metrics, but none exist for echocardiography. To address this, we developed EchoGraph, a BERT-based model trained on 600 densely annotated echocardiography reports from the Mayo Clinic (2017), split…
2026-01-01 · SSRN Electronic Journal
Exploiting Structural Properties of the Allocation Subproblem in Emergency Logistics Center Location: A Dominance-Preserving Decoder and Heuristic-Priority Discrete PSO, published in SSRN Electronic Journal on 2026-01-01. Verify the complete record using the DOI link.
2026-02-24 · arXiv (Cornell University)
Embodied LLMs endow robots with high-level task reasoning, but they cannot reflect on what went wrong or why, turning deployment into a sequence of independent trials where mistakes repeat rather than accumulate into experience. Drawing…
2026-03-17 · medRxiv
Echocardiography is the most widely used cardiac imaging modality, yet artificial intelligence-enabled interpretation remains limited by the inability of existing models to integrate visual assessment, quantitative measurement, and clinical reasoning within a unified framework. Here…
2026-07-21 · Scientific Journal of Economics and Management Research
As one of the compulsory basic general education courses in China’s higher education institutions, College English focuses on cultivating moral integrity and nurturing talents, and promotes overall improvement in foreign language proficiency and intercultural competence.…
2026-07-26 · Scientific Journal Of Humanities and Social Sciences
The three basic parts of undergraduate critical thinking in academic study are the focus of this paper. I will concentrate on students' ability to put forward good research questions, construct reasonable academic arguments, and use…
2026-06-18 · Nature Biotechnology
In the version of the article initially published, in the “Directed evolution of GeoCas9” section of the Methods, the text “After recovery of the electroporated bacteria in 750 µl of sulfur-oxidizing bacteria for 1.5 h…
2026-06-19 · bioRxiv (Cold Spring Harbor Laboratory)
Abstract Packaging of viral genomes into progeny virions is a critical step in the viral life cycle. Coronaviruses such as SARS-CoV-2 possess unusually large RNA genomes (∼30 kb), yet the mechanism by which these genomes…
2026-06-23 · bioRxiv (Cold Spring Harbor Laboratory)
Therapeutic genome editing requires delivery of editing molecules to defined cell types, but targeting specificity and efficiency are currently limited. We hypothesized that properties inherent to immune cells, including tissue infiltration and programmed cell recognition,…
2026-07-01 · Nature
Harmonizing standards and resources for the medical genome, published in Nature on 2026-07-01. Verify the complete record using the DOI link.
2026-07-16 · Science
The design of RNA-guided nucleases with properties not limited by evolution can expand programmable genome-editing capabilities. However, generating diverse multidomain proteins with robust enzymatic properties remains challenging. Here, we use a protein design strategy that…
2026-08-01 · Molecular Cell
Stepwise DNA-unwinding gates TnpB genome-editing activity, published in Molecular Cell on 2026-08-01. Verify the complete record using the DOI link.
2026-08-11 · bioRxiv (Cold Spring Harbor Laboratory)
Summary The therapeutic potential of CRISPR–Cas9 genome editing is fundamentally constrained by the requirement for specific short DNA sequences (PAMs) flanking the target site, limiting access to many clinically relevant genomic loci. This stringent PAM…
2026-08-14 · Nature
Publisher Correction: Targeting cancer-specific mutations with RNA-triggered chromatin shredding, published in Nature on 2026-08-14. Verify the complete record using the DOI link.