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MRS CLEAN: A Synthetic Tabular Dataset of Stroke Patients based on the MR CLEAN Trials

MRS CLEAN This repository contains a synthetic tabular dataset of stroke patients based on the MR CLEAN Registry and MR CLEAN-LATE, MR CLEAN-MED and MR CLEAN-NOIV trials. We evaluated multiple synthetic data generation methods and found that TabDDPM works best, generating data that is st

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Creatorte Nijenhuis, Frank
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Published2026-03-03
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DOI10.5281/zenodo.18846304
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Downloads24
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Licensezenodo-freetoread-1.0
Data TypeDataset
Published2026
Licensezenodo-freetoread-1.0
Total Views1,069
Total Downloads24

MRS CLEAN

This repository contains a synthetic tabular dataset of stroke patients based on the MR CLEAN Registry and MR CLEAN-LATE, MR CLEAN-MED and MR CLEAN-NOIV trials. We evaluated multiple synthetic data generation methods and found that TabDDPM works best, generating data that is statistically similar to the real data. On a functional outcome prediction task, prediction models trained on synthetic data show similar performance to models trained on real data when evaluating on a (real) held out test set.

For more information on the development of the TabDDPM model, we refer to our preprint.

Variable Codebook:

Variable codenameHuman‑readable nameDatatypePossible valuesInterpretationDistribution
StudySubjectIDStudy subject identifierstringS0000–S14999Unique patient identifiern=15,000, all unique
r_ageAge (years)integer25–93Age at stroke onset72 (64–81)
r_sexSexbinary0, 10 = male, 1 = female0: 48.7%, 1: 51.3%
bl_NIHSS_sumscoreBaseline NIHSS scoreinteger0–42National Institutes of Health Stroke Scale; stroke severity (higher = worse)15 (11–20)
bl_phy_rrsystBaseline systolic blood pressure (mmHg)integer~90–250Systolic BP at baseline150 (134–167)
bl_phy_rrdiastBaseline diastolic blood pressure (mmHg)integer~45–185Diastolic BP at baseline82 (73–91)
bl_lab_glucoseBaseline blood glucose

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Files are hosted on the source repository. Click download to access the full dataset.

te Nijenhuis, Frank (2026). MRS CLEAN: A Synthetic Tabular Dataset of Stroke Patients based on the MR CLEAN Trials. https://doi.org/10.5281/zenodo.18846304