PCUK2023 FTIR Prostate TMA Dataset

Dataset Contents

This dataset contains 1045 Fourier Transform Infrared (FTIR) images of prostate tissue micro-array (TMA) cores from a set of 21 TMA slides and a total of 181 unique patients.

Each TMA core in this dataset has associated with it the following data:

• FTIR Image in hdf5 format [256 x 256 x 1479]
• Greyscale ‘chemical’ image calculated as the area under the Amide I spectral band [256 x 256 x 3]
• Binary tissue/background mask [256 x 256 x 3]
• H&E image from a serial section, aligned with the FTIR [1024 x 1024 x 3]
• Core-level cancer/benign labels
• Core-level Gleason grading
• Patient ID
• Patient-level TNM cancer staging

The file ‘master_sheet.xlsx’ contains a reference of every TMA core’s name and its associated metadata. Files in this dataset are in the format s<slide_id>_c<core_id>.<file_extension>. The file ‘wavenumbers.h5’ contains the exact wavenumber values corresponding to each of the 1479 channels in the FTIR images.

Tissue Annotation

A subset of 227 TMA cores spanning 100 patients in this dataset have sparse pixel-level annotations of the following tissue types: