Academic Journal
Q1European Journal of Medicinal Chemistry
About European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry is a scholarly journal published by Elsevier Masson s.r.l.. SCImago 2025 places it in Q1 with an SJR of 1.152 and an H-index of 225.
Its listed coverage is 1974-2026 and its research categories include Drug Discovery (Q1); Medicine (miscellaneous) (Q1); Organic Chemistry (Q1); Pharmacology (Q1). The 2025 dataset reports 975 documents and 17444 citations across the latest three-year reporting window.
Journal Metrics
Metrics can change by reporting year. Verify time-sensitive values with the publisher or indexing service.
Aims & Scope
The journal publishes research related to Synthesis and biological activity, Synthesis and Biological Evaluation, Cancer therapeutics and mechanisms, Computational Drug Discovery Methods, Click Chemistry and Applications, Bioactive Compounds and Antitumor Agents.
Recent Research Articles
Latest publications matched automatically by ISSN.
Discovery of chromone-derived EGFR inhibitors as potent apoptosis inducers in cancer: In vitro and in vivo insights
Amr Elagamy, Mohamed S. Nafie, Ahmed Elnahrawy, Mohamed Elsayed et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119219Optimization of covalent pan-fibroblast growth factor receptor inhibitors for treating solid tumors
Shihe Hu, Cuihua Jiang, Xiaoyang Zhang, Ke Chen et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119246Precision chemoenzymatic tailoring of bioengineered low-molecular-weight heparins for protamine-reversible anticoagulation
Lin Wang, Yali Wang, Fengyan Tang, Yanzhen Cheng et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119275Novel far-red fluorescent theranostic probes for selective imaging and targeted therapy of BET proteins in breast cancer
Yuqi Gao, Wenjie Liu, Xuerui Zhang, Leyan Qin et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119325Integrated experimental and computational investigation of sophoridine derivatives reveals antitumor potential and Topo I-associated mechanisms
Ya-Kun Zhang, Jian-Bo Tong, Hong-Yan Zhang, Zhi-Peng Qin et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119232Discovery of a brain penetrant NLRP3 inflammasome inhibitor that reduces neuropathic pain in mice
Yiming Xu, Jannatun Namme, Liuyue Yang, Yulong Xu et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119319Synthesis and biological activity of steroid conjugates of five-membered N-heterocycles with one or two nitrogen atoms: A review covering the years 2020-2025
Ali Abbas Abo Algon, Rita Skoda-Földes
2026-12 · DOI: 10.1016/j.ejmech.2026.119300Discovery of piperazine-based multi-site occupying coronavirus Mpro inhibitors with potent and broad-spectrum antiviral activity
Bing Ye, Myoung Kyu Lee, Letian Song, Yeon Seo Jeon et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119248Design, synthesis, and biological evaluation of benzoisonicotinamide derivatives as novel xanthine oxidase inhibitors guided by metabolic stability
Gong-hui Ge, Shuai Guo, Wen-hui Yu, Li-rong Liu et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119214Cationic metal-binding coumarin amphiphiles as membrane-active antimicrobial agents
Samuel O. Nitschke, Anteneh Amsalu, Muhammed Awad, Alysha G. Elliott et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119245Targeting the myeloid immune checkpoint ILT3 (LILRB4) with small molecules enables reprogramming of suppressive tumor immunity
Somaya A. Abdel-Rahman, Antonio Monari, Tom Miclot, Florent Barbault et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119295Cysteine-targeting covalent inhibition: Recent trends and emerging strategies
Mariana Castelôa, Fernanda Borges, Sofia Benfeito, Daniel Chavarria et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119264Small-molecule inhibitors of SGK1: Structural basis, structure-activity relationships, and therapeutic perspectives
Jingjing Xie, Wu Wu, Guonian Zhu, Jinghong Xian et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119253Critical structural insights into selective small-molecule and peptide inhibitors of human urokinase-type plasminogen activator
Donata Pluskota-Karwatka, Dariusz Wawrzyniak, Jakub Nowicki, Klaudia Jaworska et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119251Adaptive prioritized expansion for cost-conscious retrosynthetic route planning
Shuan Liu, Jingwen Wang, Shaoye Zhang, Jianbo Qiao et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119309Discovery of pyridine formyl hydrazide derivatives as potent non-nucleoside RSV polymerase inhibitors
Xin Li, Jinyuan Wu, Lin Zheng, Sining Tao et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119256Structure-based virtual screening leads to the discovery of a 4,5-dihydropyrazole derivative as the first dual inhibitor of West Nile virus NS3 helicase and protease
Antonio Lupia, Roberta Emmolo, Giulia Atzeni, Erica Sanna et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119273Synthesis and biological evaluation of novel gemcitabine-dexamethasone hybrid as potent antitumor agents against esophageal cancer
Ruoxin Liu, Na Liu, Yimeng Wang, Jingyu Yang et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119252Carborane-modified paclitaxel analogues: Position-dependent modulation of mitotic catastrophe and lysosomal function
Sebastian Rykowski, Daria Różycka, Marta Orlicka-Płocka, Dorota Gurda-Woźna et al.
2026-12 · DOI: 10.1016/j.ejmech.2026.119244Development of mitochondria-targeted isoquinolinium derivatives with dual fluorescence and anticancer activity against KRAS-mutant NSCLC
Iria Alonso-Alves, Ana Conejo-García, Belén Rubio-Ruiz
2026-12 · DOI: 10.1016/j.ejmech.2026.119225Reviews
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September 8, 2026 at 12:09 am
September 8, 2026