
Academic Journal
Q1Molecular Therapy Methods and Clinical Development
About Molecular Therapy Methods and Clinical Development
Molecular Therapy Methods and Clinical Development is a scholarly journal published by Cell Press. SCImago 2025 lists it in Q1, with an SJR of 1.749 and H-index of 77.
Coverage: 2014-2025. Research categories: Genetics (Q1); Molecular Biology (Q1); Molecular Medicine (Q1).
Open-access policies and author information
Reported in the official DOAJ public CSV snapshot (2026-09-01), downloaded 2026-10-03. Record updated 2026-04-27. This snapshot does not establish today’s listing status or fee quotation.
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Source-backed journal facts
Topics in published research
Virus-based gene therapy research; CRISPR and Genetic Engineering; CAR-T cell therapy research; RNA Interference and Gene Delivery; Viral Infectious Diseases and Gene Expression in Insects; Viral Infections and Immunology Research.
OpenAlex classifies topics from published works. These topics are not the publisher’s official aims and scope.
Source: OpenAlex source record. Retrieved 2026-10-03. Source record updated 2026-10-02. OpenAlex metrics are different from SCImago metrics and the Clarivate Journal Impact Factor.
Journal Metrics
Quartile, SJR and the listed SCImago H-index use the 2025 imported SCImago dataset. A quartile may vary by subject category. Values without a source or reporting year are unverified historical entries. Verify the current Journal Impact Factor with Clarivate or the publisher before using it.
Aims & Scope
The publisher’s official aims and scope have not yet been verified for this profile. Use the journal website to check subject fit and accepted article types before submitting.
Recent Research Articles
Latest publications matched automatically by ISSN.
When pullulanase needs a little push: MyoAAV capsids enhance gene therapy for GSD IIIa
Sree Venigalla, Christina A. Pacak
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Thomas M. Leibiger, Lie Min, Kelvin H. Lee
2025-12 · DOI: 10.1016/j.omtm.2025.101623Nonclinical toxicity study duration in AAV gene therapy development: Evidence from industry survey supports adequacy of short-term assessments
Basel T. Assaf, David Edwards, Shawn Jay Berens, Brian Lauritzen et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101628Generation of high-quality single-stranded DNA for full-length and truncated genome standards of recombinant adeno-associated viruses
Julia Manz, Raphael Ruppert, Markus Haindl, Jürgen Hubbuch et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101603Leveraging the active conformation of LFA-1 as a potential target for hematological malignancies
Abhishek Puthenveetil, Guy Biber, Batel Sabag, Meirav Kedmi et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101632Comparative analysis of cell-specific promoters in AAV9-mediated gene therapy targeting the central nervous system
Sergiy Chornyy, Jessica A. Herstine, Caleb Holaway, Abigail Biddle et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101588SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production
Rodrigo José Nogueira, Ana Filipa Rodrigues, Daniel Alexandre Mestre, Ana Sofia Coroadinha et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101619Rapid kinetics of AAV8 delivery of Vglut3 and hearing rescue shown day-by-day via matched IHC and ABR
Cole W.D. Peters, Killian Hanlon
2025-12 · DOI: 10.1016/j.omtm.2025.101638Retinal organoids mirror CRISPR-Cas9 gene editing efficiency observed in vivo
Juliette Pulman, Hugo Malki, Paul Oudin, Ecem Aydin et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101627From cold chain to ambient: Benefits, risks, and evidence across cell therapy logistics
John Gostage, Daniel A. Domingo-Lopez, Ruth Tarpey, Garry P. Duffy et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101613Modified AAV5 capsid for improved brain biodistribution following direct injection in preclinical models
Sebastian N. Kieper, Elisabeth A. Spronck, Meriem Bourajjaj, Roberto D.V.S. Morais et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101642Safety and efficacy of AAV8-aflibercept in treating choroidal neovascularization via single-cell RNA sequencing
Jiemei Shi, Kaicheng Wu, Lihui Chen, Yinling Li et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101625Design of cationic ionizable lipids for the delivery of therapeutic nucleic acids
N. D. Prasad Atmuri, Fariba Saadati, Jayesh Kulkarni, Dominik Witzigmann et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101585Landscape of ex vivo gene therapies: Technological trends and future prospects
Aline Almeida-Oliveira, Martín Hernán Bonamino, Marisol Simões, Vitor Hugo Villaça Martins et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101580A potency and toxicology study on tolerability of cryopreserved mesenchymal stem cell product with DMSO in septic mice and nude rats
Yan Wang, Glinton Hanover, Aidan B.P. Murray, Mahmoud Salkhordeh et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101611From rough to refined: Applying diamond standards to CAR Treg development
Francesco W. Hamilton, Leonardo M.R. Ferreira
2025-12 · DOI: 10.1016/j.omtm.2025.101604Lactic acid improves Treg manufacturing and in vivo function
Karoliina Tuomela, Emily S.Y. Leong, Manjurul Haque, Sonya Mangat et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101600Unveiling genomic rearrangements in engineered iPSC lines by optical genome mapping
Darren Finlay, Pooja Hor, Benjamin H. Goldenson, Xiao-Hua Li et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101644Systemic mRNA-LNP administration in fetuses improves survival in a mouse model of spinal muscular atrophy
Marco D. Carpenter, Nicole Kus, Rosa B. Choi, Hooda Said et al.
2025-12 · DOI: 10.1016/j.omtm.2025.101599Characterization of adeno-associated viral transduction of retinal ganglion cells in adult and old mice
Delaney CM. Henderson, Balwantray C. Chauhan
2025-12 · DOI: 10.1016/j.omtm.2025.101595Reviews
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Version History
October 4, 2026 at 8:49 pm
September 25, 2026