SCHOLARLY PUBLICATION

Clustal Omega

Fabian Sievers, Desmond G. Higgins

📖 Current Protocols in Bioinformatics → 📅 2014-12-01 🔗 DOI: 10.1002/0471250953.bi0313s48

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📄 Abstract

Clustal Omega is a package for making multiple sequence alignments of amino acid or nucleotide sequences, quickly and accurately. It is a complete upgrade and rewrite of earlier Clustal programs. This unit describes how to run Clustal Omega interactively from a command line, although it can also be run online from several sites. The unit describes a basic protocol for taking a set of unaligned sequences and producing a full alignment. There are also protocols for using an external HMM or iteration to help improve an alignment.

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