Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTEnzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of CancerWilliam B. Parker*†View Author Information Southern Research Institute, 2000 Ninth Avenue, South Birmingham, Alabama 35205* E-mail: [email protected]. Tel.: 205-581-2797. Fax: 205-581-2447.†Disclosure: Dr. Parker has a financial interest in clofarabine, thio-araC, and the E. coli PNP gene therapy strategy for the treatment of cancer.Cite this: Chem. Rev. 2009, 109, 7, 2880–2893Publication Date (Web):May 29, 2009Publication History Received23 January 2009Published online29 May 2009Published inissue 8 July 2009https://doi.org/10.1021/cr900028pCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views5730Altmetric-Citations426LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (1 MB) Get e-AlertscloseSUBJECTS:Cells,Genetics,Inhibition,Nucleic acids,Peptides and proteins Get e-Alerts