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Luminescent Gold Nanoparticles with Efficient Renal Clearance

Chen Zhou, Michael Long, Yanping Qin, Xiankai Sun, Jie Zheng

📖 Angewandte Chemie International Edition → 📅 2011-03-04 🔗 DOI: 10.1002/anie.201007321

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📄 Abstract

Going to waste: Renal clearance of 2 nm glutathione-coated luminescent gold nanoparticles (GS-AuNPs) was more than 10 to 100 times better than that of the similarly sized nonluminescent AuNPs coated by bis(p-sulfonatophenyl)phenylphosphine and cysteine. Urinary excretion of the particles was imaged with X-ray computed tomography (see picture of a mouse after injection of GS-AuNPs) and luminescence techniques in real time.

📄 Abstract

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