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SCHOLARLY PUBLICATION ✓ Open Access

Nanoscale magnetic resonance imaging

Christian Lukas Degen, Martino Poggio, H. Jonathon Mamin, Charles T. Rettner, D. Rugar

📖 Proceedings of the National Academy of Sciences → 📅 2009-01-12 🔗 DOI: 10.1073/pnas.0812068106
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📄 Abstract

We have combined ultrasensitive magnetic resonance force microscopy (MRFM) with 3D image reconstruction to achieve magnetic resonance imaging (MRI) with resolution <10 nm. The image reconstruction converts measured magnetic force data into a 3D map of nuclear spin density, taking advantage of the unique characteristics of the "resonant slice" that is projected outward from a nanoscale magnetic tip. The basic principles are demonstrated by imaging the (1)H spin density within individual tobacco mosaic virus particles sitting on a nanometer-thick layer of adsorbed hydrocarbons. This result, which represents a 100 million-fold improvement in volume resolution over conventional MRI, demonstrates the potential of MRFM as a tool for 3D, elementally selective imaging on the nanometer scale.

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