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SCHOLARLY PUBLICATION ✓ Open Access

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender, Mudra Hegde, Emma W Vaimberg, Katherine F. Donovan, Ian C. P. Smith, Zuzana Tóthová, Craig B. Wilen, Robert C. Orchard, Herbert W. Virgin, Jennifer Listgarten, David E. Root

📖 Nature Biotechnology → 📅 2016-01-18 🔗 DOI: 10.1038/nbt.3437
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