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Sex and gender differences in autism spectrum disorder: summarizing evidence gaps and identifying emerging areas of priority

Alycia K. Halladay, Somer L. Bishop, John Nicholas Constantino, Amy M. Daniels, Katheen Koenig, Kate Palmer, Daniel S. Messinger, Kevin Archer Pelphrey, Stephan Sanders, Alison Singer, Julie Lounds Taylor, Péter Szatmári

📄 Abstract

One of the most consistent findings in autism spectrum disorder (ASD) research is a higher rate of ASD diagnosis in males than females. Despite this, remarkably little research has focused on the reasons for this disparity. Better understanding of this sex difference could lead to major advancements in the prevention or treatment of ASD in both males and females. In October of 2014, Autism Speaks and the Autism Science Foundation co-organized a meeting that brought together almost 60 clinicians, researchers, parents, and self-identified autistic individuals. Discussion at the meeting is summarized here with recommendations on directions of future research endeavors.

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