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Single Continuous Wave Laser Induced Photodynamic/Plasmonic Photothermal Therapy Using Photosensitizer‐Functionalized Gold Nanostars

Shouju Wang, Peng Huang, Liming Nie, Ruijun Xing, Dingbin Liu, Zhe Wang, Jing Lin, Shuiliang Chen, Gang Niu, Guangming Lu, Xiaoyuan Chen

📖 Advanced Materials → 📅 2013-02-13 🔗 DOI: 10.1002/adma.201204623

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📄 Abstract

Chlorin e6 conjugated gold nanostars (GNS-PEG-Ce6) are used to perform simultaneous photodynamic/plasmonic photothermal therapy (PDT/PPTT) upon single laser irradiation. The early-phase PDT effect is coordinated with the late-phase PPTT effect to obtain synergistic anticancer efficiency. The prepared GNS-PEG-Ce6 shows excellent water dispersibility, good biocompatibility, enhanced cellular uptake and remarkable anticancer efficiency upon irradiation in vivo.

📄 Abstract

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