Skip to content
JournalsWorldThe Global Research Discovery Platform
SCHOLARLY PUBLICATION ✓ Open Access

The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations

Martin O. Leach, Kevin Michael Brindle, Jeff Evelhoch, John Richard Griffiths, Michael R. Horsman, Alan Jackson, Gordon C. Jayson, Ian Robert Judson, Michael Vinzenz Knopp, R. J. Maxwell, Dominick J. O. McIntyre, Anwar R. Padhani, Pat Price, R Rathbone, Gordon J.S. Rustin, Paul S. Tofts, Gillian M. Tozer, W. Vennart, John C. Waterton, S. R. Williams, Paul Workman

📄 Abstract

Vascular and angiogenic processes provide an important target for novel cancer therapeutics. Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to noninvasively monitor the action of these therapeutics in early-stage clinical trials. This publication reports the outcome of a workshop that considered the methodology and design of magnetic resonance studies, recommending how this new tool might best be used.

📤 Share this page

Found this useful? Share it with your network.

✓ Link copied! Paste it on ResearchGate / Academia.edu