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The many faces of the anti-COVID immune response

Santosha Adipudi Vardhana, Jedd D. Wolchok

📖 The Journal of Experimental Medicine 📅 2020-04-28 🔗 DOI: 10.1084/jem.20200678

📄 Abstract

The novel 2019 strain of coronavirus is a source of profound morbidity and mortality worldwide. Compared with recent viral outbreaks, COVID-19 infection has a relatively high mortality rate, the reasons for which are not entirely clear. Furthermore, treatment options for COVID-19 infection are currently limited. In this Perspective, we explore the contributions of the innate and adaptive immune systems to both viral control as well as toxicity during COVID-19 infections and offer suggestions to both understand and therapeutically modulate anti-COVID immunity.

📄 Abstract

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