Academic Journal
Q1Science Signaling
About Science Signaling
Science Signaling is a scholarly journal published by American Association for the Advancement of Science. SCImago 2025 lists it in Q1, with an SJR of 2.05 and H-index of 193.
Coverage: 2000, 2008-2026. Research categories: Biochemistry (Q1); Cell Biology (Q1); Molecular Biology (Q1).
Source-backed journal facts
Topics in published research
Immune Cell Function and Interaction; Receptor Mechanisms and Signaling; T-cell and B-cell Immunology; Neuroscience and Neuropharmacology Research; Protein Kinase Regulation and GTPase Signaling; Ubiquitin and proteasome pathways.
OpenAlex classifies topics from published works. These topics are not the publisher’s official aims and scope.
Source: OpenAlex source record. Retrieved 2026-10-03. Source record updated 2026-10-02. OpenAlex metrics are different from SCImago metrics and the Clarivate Journal Impact Factor.
Journal Metrics
Quartile, SJR and the listed SCImago H-index use the 2025 imported SCImago dataset. A quartile may vary by subject category. Values without a source or reporting year are unverified historical entries. Verify the current Journal Impact Factor with Clarivate or the publisher before using it.
Aims & Scope
The publisher’s official aims and scope have not yet been verified for this profile. Use the journal website to check subject fit and accepted article types before submitting.
Recent Research Articles
Latest publications matched automatically by ISSN.
S1P mimics phosphorylation to mediate PDK1-independent activation of aPKC with an opposing downstream effect
Taketoshi Kajimoto, Ambuj Srivastava, Jing Zhang, Taro Okada et al.
2026-09-29 · DOI: 10.1126/scisignal.adw7297Light-induced remodeling of the Drosophila phosphoproteome regulates visual adaptation through the Trp channel
Lucas D. Kramer, Tal Brandwine-Shemmer, Leah R. Pierce, Yi-Kai Liu et al.
2026-09-29 · DOI: 10.1126/scisignal.aei4151Dishevelled drives disassembly of primary cilia through an unusual PDZ domain–mediated binding mode with Girdin-L
Miha Renko, Gonzalo J. Beitia, Trevor J. Rutherford, Mariann Bienz et al.
2026-09-22 · DOI: 10.1126/scisignal.aed1808PAG supports T cell immune synapse function by binding to actin
Emily K. Moore, Shoiab Bukhari, Justin Zhong, Carly Tymm et al.
2026-09-22 · DOI: 10.1126/scisignal.aef0327How some brain macrophages go with the flow
Wei Wong
2026-09-22 · DOI: 10.1126/scisignal.aem4471The RAMP3 proximity interactor MYO6 determines spatiotemporal signaling of the GPCR CLR in lymphatic endothelial cells
D. Stephen Serafin, Monserrat Avila-Zozaya, Poonam Kumari, Natalie R. Harris et al.
2026-09-15 · DOI: 10.1126/scisignal.ady6108Viral hijacking of the host ubiquitin-proteasome system for immune escape
Junji Zhu, Michaela U. Gack
2026-09-15 · DOI: 10.1126/scisignal.aek8777Stress lends a helping hand to glioma
Leslie K. Ferrarelli
2026-09-08 · DOI: 10.1126/scisignal.aem0403Clostridioides difficile couples responses to host nutritional immunity and a commensal-derived antibiotic to enable growth in the gut
Martin V. Douglass, Lauren R. Melton, M. Wade Calcutt, Tess P. McNeely et al.
2026-09-08 · DOI: 10.1126/scisignal.aef8846Erratum for the Research Article “Adenosine 2A receptor drives microglial efferocytosis to accelerate white matter repair and functional recovery after stroke”
2026-09-08 · DOI: 10.1126/scisignal.ael5919HRAS promotes mutant NRAS–driven transformation with codon and allele specificity
Hyun Lee, Jacob M. Hughes, Joseph P. LaMorte, Bridget A. Finniff et al.
2026-09-08 · DOI: 10.1126/scisignal.aej6209ORAI Ca 2+ channels and STIM1 drive capillary-to-arteriole communication in neurovascular coupling
Boris Lavanderos, Alfredo Sanchez-Solano, Wanchun Zhu, Pratish Thakore et al.
2026-09-01 · DOI: 10.1126/scisignal.aef0939When electricity isn’t enough: ORAI channels reinforce neurovascular coupling
Fabrice Dabertrand
2026-09-01 · DOI: 10.1126/scisignal.aek0208Reexamining the activation mechanisms of adhesion G protein–coupled receptors
Demet Araç, Szymon P. Kordon
2026-09-01 · DOI: 10.1126/scisignal.aeg6095BRAF recruitment to spinal sensory synapses promotes neuropathic pain by potentiating transsynaptic NMDA receptor activity
Daozhong Jin, Hong Chen, Yuying Huang, Shao-Rui Chen et al.
2026-08-25 · DOI: 10.1126/scisignal.aeh6852Fat-fighting club cells
Annalisa M. VanHook
2026-08-25 · DOI: 10.1126/scisignal.ael6285Distinct properties of glutamate-dopamine, nonglutamate-dopamine, and glutamate-only ventral tegmental area neurons
Emily D. Prévost, Lucy A. Ward, Daniel Alas, Giulia A. Aimale et al.
2026-08-18 · DOI: 10.1126/scisignal.aee2028A genome-wide map of the genetic network in monocytes that regulates type I interferon induction by the cGAS-STING pathway
Emil Aagaard Thomsen, Jian Zhao, Ryo Narita, Luther J. Davis et al.
2026-08-18 · DOI: 10.1126/scisignal.adx3808Beyond the scaffold: Glia as architects of the neural extracellular matrix
John Lenon de Souza Santos, Dolores Irala
2026-08-11 · DOI: 10.1126/scisignal.aeh8955LRP5-dependent transport of polyunsaturated fatty acids serves as an immune checkpoint for natural killer cells
Yi Luan, Chuan Yang, Hongyue Zhou, Zhuo Chen et al.
2026-08-11 · DOI: 10.1126/scisignal.ady2865Reviews
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September 25, 2026 at 7:10 am
September 25, 2026