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Andrew Z. Fire

American biologist and professor of pathology and genetics

Stanford Medicine

Stanford, CA

Andrew Zachary Fire is an American biologist and professor of pathology and of genetics at the Stanford University School of Medicine. He was awarded the 2006 Nobel Prize in Physiology or Medicine, along with Craig C. Mello, for the discovery of RNA interference (RNAi). This research was conducted at the Carnegie Institution of Washington and published in 1998.

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Publications298Total indexed works
Citations55,346Source-reported citations
h-index89Source-reported h-index
i10-index177Source-reported i10-index

Biography, research & contributions

Andrew Zachary Fire is an American biologist and professor of pathology and of genetics at the Stanford University School of Medicine. He was awarded the 2006 Nobel Prize in Physiology or Medicine, along with Craig C. Mello, for the discovery of RNA interference (RNAi). This research was conducted at the Carnegie Institution of Washington and published in 1998.

Affiliation

Stanford Medicine

Top Publications

  • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans (1998) - 15,602 citations
  • Specific interference by ingested dsRNA (1998) - 1,968 citations
  • Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans (2001) - 1,906 citations
  • Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing (2001) - 1,898 citations
  • The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans (1999) - 1,328 citations

At a glance

Full name
Andrew Z. Fire
Born
1959-04-27
ORCID
0000-0001-6217-8312
OpenAlex ID
https://openalex.org/A5057231025

Research interests

  • Genomics and Chromatin Dynamics, Chromosomal and Genetic Variations, Genomics and Phylogenetic Studies, Developmental Biology and Gene Regulation, RNA Interference and Gene Delivery

Research topics

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Education

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Selected research & further reading

A curated reading list, not a ranking by citation count. References use DOI metadata, matching public scholarly records or authoritative lecture sources.

    See the source-linked reading and original works in the research guide above.

    Citation & publication trends

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    Source: OpenAlex · Retrieved 2026-10-07. Metrics are database-specific and are not a scientific ranking.

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    Institutions

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    Awards & honors

    • Nobel Prize in Physiology or Medicine (2006) — for their discovery of RNA interference - gene silencing by double-stranded RNA

    Career timeline

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    Co-authors

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    Education & career institution links

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    Sources & data information

    Editorial review: 2026-10-07 · Last data update: 2026-10-07 23:49:39

      Unknown values are left blank. Linked publications may be a subset of total works. Identity verification, data retrieval and profile ownership are separate checks.

      Cite this profile

      Andrew Z. Fire. JournalsWorld. Accessed October 9, 2026.

      https://journalsworld.com/researchers/andrew-z-fire/