Bart De Strooper
The Francis Crick Institute
Bart De Strooper is a Belgian molecular biologist and professor at Vlaams Instituut voor Biotechnologie and KU Leuven and the UK Dementia Research Institute and University College London, UK. De Strooper's research seeks to translate genetic data into the identification and treatment of neurodegenerative diseases and treatments. interest are the secretases, proteases which cleave the amyloid precursor protein (APP), resulting in amyloid peptides.
Read biography ↓Biography, research & contributions
Bart De Strooper is a Belgian molecular biologist and professor at Vlaams Instituut voor Biotechnologie and KU Leuven and the UK Dementia Research Institute and University College London, UK. De Strooper's research seeks to translate genetic data into the identification and treatment of neurodegenerative diseases and treatments. interest are the secretases, proteases which cleave the amyloid precursor protein (APP), resulting in amyloid peptides.
Affiliation
The Francis Crick Institute
Top Publications
- Alzheimer's disease (2021) - 5,305 citations
- Alzheimer's disease (2016) - 3,187 citations
- Reactive astrocyte nomenclature, definitions, and future directions (2021) - 2,533 citations
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics (2011) - 2,256 citations
- A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain (1999) - 2,128 citations
At a glance
- Full name
- Bart De Strooper
- ORCID
- 0000-0001-5455-5819
- OpenAlex ID
- https://openalex.org/A5021772353
Research interests
- Alzheimer's disease research and treatments, Neuroinflammation and Neurodegeneration Mechanisms, Dementia and Cognitive Impairment Research, Neuroscience and Neuropharmacology Research, Protease and Inhibitor Mechanisms
Research topics
Education
Not yet documented in this profile.
Selected research & further reading
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See the source-linked reading and original works in the research guide above.
Citation & publication trends
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Source: OpenAlex · Retrieved 2026-10-07. Metrics are database-specific and are not a scientific ranking.
Most-cited linked publications
Publications matched across ORCID and OpenAlex. Citation counts are source-specific.
- Alzheimer's disease ↗2021 · The Lancet5,305OpenAlex citations
- Alzheimer's disease ↗2016 · The Lancet3,187OpenAlex citations
- Reactive astrocyte nomenclature, definitions, and future directions ↗2021 · Nature Neuroscience2,533OpenAlex citations
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics ↗2011 · Nature Reviews Drug Discovery2,256OpenAlex citations
- 2,128OpenAlex citations
Recent linked publications
Publications matched across ORCID and OpenAlex. Citation counts are source-specific.
- Alzheimer's disease ↗2021 · The Lancet
- Alzheimer's disease ↗2016 · The Lancet
- Reactive astrocyte nomenclature, definitions, and future directions ↗2021 · Nature Neuroscience
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics ↗2011 · Nature Reviews Drug Discovery
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Institutions
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Previous institutions
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Awards & honors
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Career timeline
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Co-authors
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Education & career institution links
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Sign in to claim this profileSources & data information
Editorial review: 2026-10-07 · Last data update: 2026-10-07 21:09:08
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