Helen S. Mayberg
Emory University
Helen S. Mayberg, is an American neurologist. Mayberg is known in particular for her work delineating abnormal brain function in patients with major depression using functional neuroimaging. This work led to the first pilot study of deep brain stimulation (DBS), a reversible method of selective modulation of a specific brain circuit, for patients with treatment-resistant depression. As of August 2019, she has published 211 original peer-reviewed articles, 31 books and book chapters, and acted as
Read biography ↓Biography, research & contributions
Helen S. Mayberg, is an American neurologist. Mayberg is known in particular for her work delineating abnormal brain function in patients with major depression using functional neuroimaging. This work led to the first pilot study of deep brain stimulation (DBS), a reversible method of selective modulation of a specific brain circuit, for patients with treatment-resistant depression. As of August 2019, she has published 211 original peer-reviewed articles, 31 books and book chapters, and acted as principal investigator on 24 research grants. Mayberg is coinventor with Andres Lozano of “Method for Treating Depression Mood Disorders and Anxiety Disorders using Neuromodulation,” US patent 2005/0033379A1. St. Jude Medical Neuromodulation licensed her intellectual property to develop Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression for the treatment of severe depression. As of 2018, Mayberg holds positions as Professor of Neurology and Neurosurgery and Professor, Psychiatry and Neuroscience, both at Mount Sinai Medical School, and Professor of Psychiatry, Emory University; Emory University Hospital. Since 2018, she has served as Director, Nash Family Center for Advanced Circuit Therapeutics at the Icahn School of Medicine at Mount Sinai.
Affiliation
Emory University
Top Publications
- Deep Brain Stimulation for Treatment-Resistant Depression (2005) - 4,148 citations
- Toward discovery science of human brain function (2010) - 3,103 citations
- Reciprocal Limbic-Cortical Function and Negative Mood: Converging PET Findings in Depression and Normal Sadness (1999) - 2,450 citations
- Resting-state connectivity biomarkers define neurophysiological subtypes of depression (2016) - 2,305 citations
- A whole brain fMRI atlas generated via spatially constrained spectral clustering (2011) - 1,748 citations
At a glance
- Full name
- Helen S. Mayberg
- ORCID
- 0000-0002-1672-2716
- OpenAlex ID
- https://openalex.org/A5026199142
Research interests
- Neurological disorders and treatments, Treatment of Major Depression, Transcranial Magnetic Stimulation Studies, Obsessive-Compulsive Spectrum Disorders, Functional Brain Connectivity Studies
Research topics
Education
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Selected research & further reading
A curated reading list, not a ranking by citation count. References use DOI metadata, matching public scholarly records or authoritative lecture sources.
See the source-linked reading and original works in the research guide above.
Citation & publication trends
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Source: OpenAlex · Retrieved 2026-10-07. Metrics are database-specific and are not a scientific ranking.
Most-cited linked publications
Publications matched across ORCID and OpenAlex. Citation counts are source-specific.
- 4,148OpenAlex citations
- Toward discovery science of human brain function ↗2010 · Proceedings of the National Academy of Sciences3,103OpenAlex citations
- Reciprocal Limbic-Cortical Function and Negative Mood: Converging PET Findings in Depression and Normal Sadness ↗1999 · American Journal of Psychiatry2,450OpenAlex citations
- Resting-state connectivity biomarkers define neurophysiological subtypes of depression ↗2016 · Nature Medicine2,305OpenAlex citations
- A whole brain fMRI atlas generated via spatially constrained spectral clustering ↗2011 · Human Brain Mapping1,748OpenAlex citations
Recent linked publications
Publications matched across ORCID and OpenAlex. Citation counts are source-specific.
- Toward discovery science of human brain function ↗2010 · Proceedings of the National Academy of Sciences
- Reciprocal Limbic-Cortical Function and Negative Mood: Converging PET Findings in Depression and Normal Sadness ↗1999 · American Journal of Psychiatry
- Resting-state connectivity biomarkers define neurophysiological subtypes of depression ↗2016 · Nature Medicine
- A whole brain fMRI atlas generated via spatially constrained spectral clustering ↗2011 · Human Brain Mapping
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Institutions
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Awards & honors
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Career timeline
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Co-authors
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Sign in to claim this profileSources & data information
Editorial review: 2026-10-07 · Last data update: 2026-10-07 23:17:44
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