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James E. Bradner

Novartis (Switzerland)

Affiliation Novartis (Switzerland) Top Publications Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers (2013) – 3,169 citations BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc (2011) – 2,894 citations RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia (2011) – 1,902 citations Phthalimide conjugation as a strategy for in ... <a title="James E. Bradner" class="read-more" href="https://journalsworld.com/researchers/james-e-bradner/" aria-label="Read more about James E. Bradner">Read more</a>

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Publications553Total indexed works
Citations59,085Source-reported citations
h-index115Source-reported h-index
i10-index226Source-reported i10-index

Biography, research & contributions

Affiliation

Novartis (Switzerland)

Top Publications

  • Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers (2013) - 3,169 citations
  • BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc (2011) - 2,894 citations
  • RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia (2011) - 1,902 citations
  • Phthalimide conjugation as a strategy for in vivo target protein degradation (2015) - 1,789 citations
  • HDAC2 negatively regulates memory formation and synaptic plasticity (2009) - 1,667 citations

At a glance

Full name
James E. Bradner
ORCID
0000-0002-2718-4415
OpenAlex ID
https://openalex.org/A5110274677

Research interests

  • Protein Degradation and Inhibitors, Chromatin Remodeling and Cancer, Histone Deacetylase Inhibitors Research, Epigenetics and DNA Methylation, Acute Myeloid Leukemia Research

Research topics

Not yet documented in this profile.

Education

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Selected research & further reading

A curated reading list, not a ranking by citation count. References use DOI metadata, matching public scholarly records or authoritative lecture sources.

    See the source-linked reading and original works in the research guide above.

    Citation & publication trends

    Annual counts are not yet available from a verified author record. Explore the research guide above for the work itself; publication and citation totals depend on database coverage.

    Source: OpenAlex · Retrieved 2026-10-07. Metrics are database-specific and are not a scientific ranking.

    Journals published in

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    Related publishers

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    Institutions

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    Previous institutions

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    Awards & honors

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    Career timeline

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    Co-authors

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    Education & career institution links

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    Sources & data information

    Editorial review: 2026-10-07 · Last data update: 2026-10-07 23:28:43

      Unknown values are left blank. Linked publications may be a subset of total works. Identity verification, data retrieval and profile ownership are separate checks.

      Cite this profile

      James E. Bradner. JournalsWorld. Accessed October 8, 2026.

      https://journalsworld.com/researchers/james-e-bradner/