Jonathan S. Stamler
University Hospitals of Cleveland
Jonathan Solomon Stamler is an English-born American physician and scientist. He is known for his discovery of protein S-nitrosylation, the addition of a nitric oxide (NO) group to cysteine residues in proteins, as a ubiquitous cellular signal to regulate enzymatic activity and other key protein functions in bacteria, plants and animals, and particularly in transporting NO on cysteines in hemoglobin as the third gas in the respiratory cycle.
Read biography ↓Biography, research & contributions
Jonathan Solomon Stamler is an English-born American physician and scientist. He is known for his discovery of protein S-nitrosylation, the addition of a nitric oxide (NO) group to cysteine residues in proteins, as a ubiquitous cellular signal to regulate enzymatic activity and other key protein functions in bacteria, plants and animals, and particularly in transporting NO on cysteines in hemoglobin as the third gas in the respiratory cycle.
Affiliation
University Hospitals of Cleveland
Top Publications
- Biochemistry of Nitric Oxide and Its Redox-Activated Forms (1992) - 2,761 citations
- A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds (1993) - 2,448 citations
- Protein S-nitrosylation: purview and parameters (2005) - 2,167 citations
- Redox signaling: Nitrosylation and related target interactions of nitric oxide (1994) - 1,732 citations
- S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control (1996) - 1,614 citations
At a glance
- Full name
- Jonathan S. Stamler
- ORCID
- 0000-0002-6866-1572
- OpenAlex ID
- https://openalex.org/A5060088000
Research interests
- Nitric Oxide and Endothelin Effects, Redox biology and oxidative stress, Hemoglobin structure and function, Heme Oxygenase-1 and Carbon Monoxide, Cardiac Ischemia and Reperfusion
Research topics
Education
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Selected research & further reading
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See the source-linked reading and original works in the research guide above.
Citation & publication trends
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Source: OpenAlex · Retrieved 2026-10-07. Metrics are database-specific and are not a scientific ranking.
Most-cited linked publications
Publications matched across ORCID and OpenAlex. Citation counts are source-specific.
- 2,761OpenAlex citations
- 2,448OpenAlex citations
- Protein S-nitrosylation: purview and parameters ↗2005 · Nature Reviews Molecular Cell Biology2,167OpenAlex citations
- 1,732OpenAlex citations
- 1,614OpenAlex citations
Recent linked publications
Publications matched across ORCID and OpenAlex. Citation counts are source-specific.
- Protein S-nitrosylation: purview and parameters ↗2005 · Nature Reviews Molecular Cell Biology
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Institutions
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Previous institutions
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Awards & honors
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Career timeline
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Co-authors
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Education & career institution links
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Sign in to claim this profileSources & data information
Editorial review: 2026-10-07 · Last data update: 2026-10-07 21:53:32
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