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Topic: COVID-19 ✕
2,640 papers on COVID-19
Most cited Newest first Oldest first
31,235 citations 🔓 OPEN ACCESS 2020
New England Journal of Medicine

Clinical Characteristics of Coronavirus Disease 2019 in China

Wei‐jie Guan, Zhengyi Ni, Yu Hu, Wenhua Liang, Chun‐Quan Ou, Jianxing He, Lei Liu, Hong Shan, Chunliang Lei, David S.C. Hui, Bin Du, Lanjuan Li, Guang Zeng, Kwok‐Yung Yuen, Ruchong Chen, Chunli Tang, Tao Wang, Pingyan Chen, Jie Xiang, Shiyue Li, Jinlin Wang, Zijing Liang, Yixiang Peng, Wei Li, Yong Liu, Yahua Hu, Peng Peng, Jianming Wang, Jiyang Liu, Zhong Chen
BACKGROUND: Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. METHODS: We extracted data regarding 1099 patients with laboratory-confirmed Covid-19…
DOI: 10.1056/nejmoa2002032 📄 PDF
19,279 citations 🔓 OPEN ACCESS 2020
DSPACE System - Metalibrary (University of the Coast)

La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19

Martínez González, Marina
El año 2020 ha sido sin duda uno que recordaremos como el más desafiante para nuestra generación, si se le observa desde una perspectiva global. Fue el año en que el mundo se confinó, mientras un virus inició una diáspora…
Jan 1, 2020 📄 PDF
17,028 citations 🔓 OPEN ACCESS 2021
Cell

Integrated analysis of multimodal single-cell data

Yuhan Hao, Stephanie Hao, Erica Andersen‐Nissen, William M. Mauck, Shiwei Zheng, Andrew W. Butler, Madeline J. Lee, Aaron J. Wilk, Charlotte A. Darby, Michael A. Zager, Paul Hoffman, Marlon Stoeckius, Efthymia Papalexi, Eleni P. Mimitou, Jaison Jain, Avi Srivastava, Tim Stuart, Lamar Ballweber-Fleming, Bertrand Z. Yeung, Angela J. Rogers, M. Juliana McElrath, Catherine A. Blish, Raphaël Gottardo, Peter Smibert, Rahul Satija
The simultaneous measurement of multiple modalities represents an exciting frontier for single-cell genomics and necessitates computational methods that can define cellular states based on multimodal data. Here, we introduce "weighted-nearest neighbor" analysis, an unsupervised framework to learn the relative utility…
DOI: 10.1016/j.cell.2021.04.048 📄 PDF
15,773 citations 🔓 OPEN ACCESS 2020
New England Journal of Medicine

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

Fernando P. Polack, Stephen James Thomas, Nicholas R.E. Kitchin, Judith Absalon, Alejandra Gurtman, Stephen P. Lockhart, John L. Perez, Gonzalo Pérez Marc, Edson Duarte Moreira, Cristiano A. F. Zerbini, Ruth E. Bailey, Kena A. Swanson, Satrajit Roychoudhury, Kenneth J. Koury, Ping Li, Warren V. Kalina, David Cooper, Robert W. Frenck, Laura L. Hammitt, Özlem Türeci, Haylene Nell, Axel Schaefer, Serhat Ünal, Dina B Tresnan, Susan Mather, Philip R. Dormitzer, Uğur Şahin, Kathrin Ute Jansen, William C. Gruber
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus disease 2019 (Covid-19) have afflicted tens of millions of people in a worldwide pandemic. Safe and effective vaccines are needed urgently. METHODS: In an ongoing multinational, placebo-controlled,…
DOI: 10.1056/nejmoa2034577 📄 PDF
11,556 citations 🔓 OPEN ACCESS 2020
New England Journal of Medicine

Dexamethasone in Hospitalized Patients with Covid-19

The RECOVERY Collaborative Group
BACKGROUND: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. METHODS: In this controlled, open-label trial comparing a range of possible treatments in patients…
DOI: 10.1056/nejmoa2021436 📄 PDF
11,210 citations 🔓 OPEN ACCESS 2020
The Lancet Infectious Diseases

An interactive web-based dashboard to track COVID-19 in real time

Ensheng Dong, Hongru Du, Lauren M. Gardner
In December, 2019, a local outbreak of pneumonia of initially unknown cause was detected in Wuhan (Hubei, China), and was quickly determined to be caused by a novel coronavirus,1 namely severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The outbreak has…
DOI: 10.1016/s1473-3099(20)30120-1 📄 PDF
10,934 citations 🔓 OPEN ACCESS 2020
New England Journal of Medicine

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

Lindsey R. Baden, Hana M. El Sahly, Brandon Essink, Karen Kotloff, Sharon Frey, Rick Novak, David Joseph Diemert, Stephen A. Spector, Nadine Rouphael, Clarence Buddy Creech, John McGettigan, Shishir Khetan, Nathan Segall, Joel Solis, Adam Brosz, Carlos Fierro, Howard Schwartz, Kathleen Neuzil, Lawrence Corey, Peter Gilbert, Holly Janes, Dean Follmann, Mary Marovich, John Mascola, Laura R. Porterfield, Julie Ledgerwood, Barney S. Graham, Hamilton Bennett, Rolando Pajon, Conor Knightly
BACKGROUND: Vaccines are needed to prevent coronavirus disease 2019 (Covid-19) and to protect persons who are at high risk for complications. The mRNA-1273 vaccine is a lipid nanoparticle-encapsulated mRNA-based vaccine that encodes the prefusion stabilized full-length spike protein of the…
DOI: 10.1056/nejmoa2035389 📄 PDF
10,302 citations 🔓 OPEN ACCESS 2020
International Journal of Environmental Research and Public Health

Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China

Cuiyan Wang, Riyu Pan, Xiaoyang Wan, Yilin Tan, Linkang Xu, Cyrus S. H. Ho, Roger Ho
Background: The 2019 coronavirus disease (COVID-19) epidemic is a public health emergency of international concern and poses a challenge to psychological resilience. Research data are needed to develop evidence-driven strategies to reduce adverse psychological impacts and psychiatric symptoms during the…
DOI: 10.3390/ijerph17051729 📄 PDF
9,909 citations 🔓 OPEN ACCESS 2020
JAMA

Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

Safiya I. Richardson, Jamie S. Hirsch, Mangala Narasimhan, James M. Crawford, Thomas G. McGinn, Karina W. Davidson, Douglas P. Barnaby, Lance B. Becker, John Chelico, Stuart L. Cohen, Jennifer Cookingham, Kevin Coppa, Michael A. Diefenbach, Andrew J. Dominello, Joan Duer-Hefele, Louise Falzon, JORDAN S. GITLIN, Negin Hajizadeh, Tiffany G. Harvin, David A. Hirschwerk, Eun Ji Kim, Zachary M. Kozel, Lyndonna M. Marrast, Jazmin N. Mogavero, Gabrielle A. Osorio, Michael Qiu, Theodoros P. Zanos
Importance: There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19). Objective: To describe the clinical characteristics and outcomes of patients with COVID-19 hospitalized in a US health care system.…
DOI: 10.1001/jama.2020.6775 📄 PDF